Tom qab mob hnyav lossis mob ntev rau cov kab mob epidermal, cov txheej txheem kho tus kheej ntawm daim tawv nqaij yuav nrawm tsim cov keratinocytes, txo lub sij hawm hloov ntawm cov hlwb epidermal, thiab kho cov tsim tawm thiab tso tawm cytokines, ua rau hyperkeratosis thiab mob me me ntawm daim tawv nqaij. . Qhov no kuj yog ib yam ntawm cov tsos mob ntawm daim tawv nqaij qhuav.
Hauv zos o tuaj yeem ua rau tawv nqaij qhuav, qhov tseeb, kev tawg ntawm epidermal barrier txhawb kev sib txuas thiab tso tawm ntawm cov kab mob pro-inflammatory cytokines, xws li IL-1he TNF, kom phagocytic immune cells, tshwj xeeb tshaj yog neutrophils, raug rhuav tshem. Tom qab tau txais kev nyiam mus rau qhov chaw qhuav, tom qab mus txog qhov chaw, neutrophils secrete leukocyte elastase, cathepsin G, protease 3, thiab collagenase rau hauv cov ntaub so ntswg, thiab tsim thiab txhawb cov protease hauv keratinocytes. Tej yam tshwm sim ntawm kev ua haujlwm protease ntau dhau: 1. Cell puas; 2. Tso tawm ntawm pro-inflammatory cytokines; 3. Kev degeneration ntxov ntxov ntawm cell-to-cell tiv tauj uas txhawb nqa cell mitosis. Proteolytic enzyme kev ua haujlwm hauv daim tawv nqaij qhuav, uas tseem tuaj yeem cuam tshuam cov paj hlwb hauv epidermis, cuam tshuam nrog pruritus thiab mob. Kev siv tshuaj pleev ib ce ntawm tranexamic acid thiab α1-antitrypsin (protease inhibitor) rau xerosis yog qhov zoo, qhia tias xeroderma cuam tshuam nrog kev ua haujlwm ntawm proteolytic enzyme.
Qhuav epidermis txhais tau tias covdaim tawv nqaij barrier yog cuam tshuam, lipids poob, proteins raug txo, thiab lub zos inflammatory yam raug tso tawm.Cov tawv nqaij qhuav tshwm sim los ntawm kev puas tsuajyog txawv los ntawm dryness los ntawm txo sebum secretion, thiab cov nyhuv ntawm yooj yim lipid supplementation feem ntau ua tsis tau raws li kev cia siab. Moisturizing tshuaj pleev ib ce tsim rau kev puas tsuaj yuav tsum tsis tsuas yog ntxiv stratum corneum moisturizing yam, xws li ceramides, ntuj moisturizing yam, thiab lwm yam, tab sis kuj coj mus rau hauv tus account cov teebmeem ntawm antioxidant, anti-inflammatory, thiab anti-cell division, yog li txo qhov sib txawv tsis tiav. ntawm keratinocytes. Barrier ntawm daim tawv nqaij qhuav yog feem ntau nrog pruritus, thiab ntxiv cov tshuaj antipruritic yuav tsum xav txog.
Lub sij hawm xa tuaj: Jun-10-2022
