Cov nyhuv tiv thaiv ntawmDaim tawv nqaij Microecologyntawm daim tawv nqaij
Cov qog sebaceous secrete lipids, uas yog metabolized los ntawm cov kab mob los tsim cov emulsified lipid zaj duab xis. Cov lipid films muaj cov roj fatty acids dawb, tseem hu ua acid films, uas tuaj yeem ua rau cov tshuaj alkaline tsis huv ntawm daim tawv nqaij thiab tiv thaiv cov kab mob txawv teb chaws (cov kab mob kis mus). , fungi thiab lwm yam kab mob pathogenic microorganisms loj hlob, yog li thawj qhov kev ua haujlwm ntawm cov tawv nqaij ib txwm muaj kev tiv thaiv tseem ceeb.
Invaginations ntawm daim tawv nqaij thiab appendages, nrog rau hws qog (cov qog hws), qog sebaceous, thiab cov hauv paus plaub hau, muaj lawv tus kheej flora. Cov qog sebaceous txuas cov hauv paus plaub hau los tsim cov follicular sebaceous chav tsev, uas zais cov lipid nplua nuj hu ua sebum. Sebum yog ib hom tshuaj tiv thaiv hydrophobic uas tiv thaiv thiab lubricates ntawm daim tawv nqaij thiab plaub hau thiab ua raws li cov tshuaj tiv thaiv kab mob. Cov qog sebaceous yog cov hypoxic, txhawb kev loj hlob ntawm cov kab mob facultative anaerobic xws liP. pob txuv, uas muaj P. acnes lipase uas degrades sebum, hydrolyzes triglycerides nyob rau hauv sebum, thiab tso tawm dawb fatty acids. Cov kab mob tuaj yeem ua raws li cov roj fatty acids dawb no, uas pab piav qhia txog kev colonization ntawm cov qog sebaceous los ntawm P. acnes, thiab cov fatty acids dawb no kuj ua rau cov kua qaub ntawm daim tawv nqaij (pH ntawm 5). Ntau cov kab mob pathogenic, xws li Staphylococcus aureus thiab Streptococcus pyogenes, yog inhibited nyob rau hauv ib qho acidic ib puag ncig thiab yog li muaj txiaj ntsig rau kev loj hlob ntawm coagulase-negative staphylococci thiab coryneform kab mob. Txawm li cas los xij, occlusion ntawm daim tawv nqaij ua rau muaj kev nce hauv pH uas yuav txhawb kev loj hlob ntawm S. aureus thiab S. pyogenes. Vim tib neeg tsim cov sebum triglycerides ntau dua li lwm cov tsiaj, ntau P. acnes colonizes tib neeg cov tawv nqaij.
Post lub sij hawm: Jun-27-2022
